Symposium "Biochemistry for Medicine" (IV-S16)

Chairs: Alexey Egorov
  Oleg Kisselev
  Serhiy Komisarenko
  Tomas Zima

July 9, 2013 METABOLISM OF CARCINOGENS AND DRUGS. FROM GENES TO CANCER AND ITS TREATMENT

Chairs: Tomas Zima, Vladimir Chekhonin

08.30 - 09.10

F. Peter Guengerich   Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee, USA

Mechanisms of activation of carcinogens by oxidations and conjugations

09.10 - 09.35

David H. Phillips   Analytical and Environmental Sciences Division, King’s College London, London, UK

Carcinogen activation in mice with genetically-altered cytochrome P450 expression

09.35 -10.00

Vladimir Chekhonin   Russian Academy of Medical Sciences, Moscow, Russia

Treatment of brain tumor by targeted cisplatin-loaded nanogels in rats

10.00 -10.25

Heinz H. Schmeiser   Research Group Genetic Alterations in Carcinogenesis, German Cancer Research Center (DKFZ), German Cancer Resesearch Center (DKFZ), Heidelberg, Germany

Metabolism of the human carcinogen aristolochic acid

10.25 – 10.50

Charles McKenna   USC Dornsife College of Letters, Arts & Sciences, Los Angeles, CA, USA

DNA polymerase beta and the BER pathway: toward a new approach to anti-cancer drug design